About me

I am a biochemist with experience studying chemokine receptors that control cell movement within the body. Chemokine receptors are members of the largest family of cell membrane bound receptors known as G-protein Coupled Receptors (GPCRs) that are targeted by nearly 50% of prescription drugs.

Studying these fascinating receptors led me to master various laboratory methods including molecular biology, mammalian tissue culture, high throughput transfection, flow cytometry, ELISA, immunofluorescence staining and Bioluminescence Resonance Energy Transfer used to monitor protein-protein interactions and conformational changes in live cells.

I am passionate about science, drug discovery, communicating science to the young and promoting the professional development of young female scientists.


EDUCATION


Ph.D. Biochemistry, Université de Montréal, Montréal, Québec, Canada 2006-2011
M.Sc. Biochemistry,Université de Montréal, Montréal, Québec, Canada 2003-2006
B.Sc. Biochemistry, Université de Montréal, Montréal, Québec, Canada 2000-2003


EXPERIENCE


Professional

Research Fellow| Principal Investigator: Dr. John H. Kehrl 2016-present
B-Cell Molecular Immunology, Laboratory of Immunoregulation
National Institute of Allergy and Infectious Diseases (NIAID)
National Institutes of Health (NIH)
Bethesda, MD

Characterization of KO mice lacking signaling proteins involved in G-Protein coupled receptors (GPCR) signaling that modulate T and B cell function.


Postdoctoral Fellow
| Principal Investigator: Dr. Thomas P. Sakmar 2011-2016
Laboratory of Chemical Biology & Signal Transduction,
The Rockefeller University, New York, NY


Characterization of the G-protein dependent and independent signaling properties of alternative splice variants of chemokine receptor CXCR3 expressed in HEK293T cells resulting in a publication currently under peer-review.

Assembled and adapted high-throughput signaling and chemotaxis assays to enable pharmacological characterization of signaling-pathway activation resulting from ligand binding to G-Protein coupled receptors (GPCR) of interest that resulted in 3 collaborations and 4 publications to be submitted for peer review in 2016.

PhD student | Principal Investigator: Dr. Nikolaus Heveker 2006-2011
Ste-Justine’s Research Centre,
Université de Montréal, Canada

Monitored conformational and functional relationships of ligand binding to chemokine receptors using Bioluminescence Resonance Energy Transfer in live cells, participated in numerous collaborations leading to 8 peer reviewed, 3 first/co-first, publications.



Business


Business Training for Scientists | SciPhD certificate 2015
Six week training covering: The business of Science, Advanced Communications, Mentoring and Delegation, Team Performance/Continuous Improvement, Project Management and Financial Literacy.

Managing Science in the Biotech Industry | BIOCOM / ASCB 2015 
One day boot camp covering: bioscience industry dynamics, processes by which scientific discoveries are translated into bioscience ventures, commercialization practices, and common business strategies within the industry.



Mentoring - The Rockefeller University 2014-2015 

I trained 2 graduate students, one from the laboratory of Lymphocyte Biology and the second from my group in the laboratory of Chemical Biology and Signal Transduction. I supervised each student in the context of their research projects and provided hands in training in studying the activation of G-protein coupled receptors.

Mentoring - Heveker Laboratory 2006-2011
I trained a total of 3 undergraduate students summer internship course BCM3532. One of these students even became a graduate student in the Heveker Laboratory. I trained 2 technician students from Saint-Jean-sur-Richelieu College’s biomedical technician program. Also, I trained 1 Ph.D. student and 2 postdoctoral fellows by sharing my BRET technology expertise.

Tutor - Department of Biochemistry / Université De Montréal 2009-2010
I assisted third year undergraduate students in one of the four section of their molecular physiology course BCM3515. Responsible of the directed migration part of the class, I helped students learn how to read a scientific paper, search the literature to answer questions about cell directed migration. I also actively participated in their evaluation.

Tutor - Department of Biochemistry / Université De Montréal 2009
I tutored undergraduate students in their class BCM1521 of introduction to laboratory work. I prepared the necessary equipment; quiz questions and supervised a total of 80 students divided in small groups. After purifying genomic DNA from calf thymus, students prepared a report in the format of a scientific paper that I evaluated.

Guest lecturer - Department of Microbiology/ Université De Montréal 2006-2010
In the immunology course MCB3964, I prepared and gave the lecture to a class of 60-80 third year undergraduate students on chemotactic cytokines. I also actively participated in formulating the exam questions as wells as corrections at the end of each semester.